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80064654 - 8th International Axon Degeneration Conference

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  • Register
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Add to Calendar 8th International Axon Degeneration Conference 9/20/2024 8:00:00 AM 9/22/2024 10:00:00 PM America/New_York For More Details: https://hopkinscme.cloud-cme.com/course/courseoverview?EID=52443 Description: Axon degeneration underlies symptoms of many neurodegenerative diseases and currently the underlying mechanisms are poorly understood and effective therapies that prevent axon degeneration are not available. The 8th Axon Degeneration Conference will bring investigators from multiple institutions together to discuss the advances made in the past 5 years in the field. The focus will be on basic mech... The Johns Hopkins Bloomberg Center located at 555 Pennsylvania NW, Washington, DC 20001 false MM/DD/YYYY


Date & Location
Friday, September 20, 2024, 8:00 AM - Sunday, September 22, 2024, 10:00 PM, The Johns Hopkins Bloomberg Center located at 555 Pennsylvania NW, Washington, DC 20001, Washington, DC

Target Audience
Specialties - Neurology

Overview
Axon degeneration underlies symptoms of many neurodegenerative diseases and currently the underlying mechanisms are poorly understood and effective therapies that prevent axon degeneration are not available. The 8th Axon Degeneration Conference will bring investigators from multiple institutions together to discuss the advances made in the past 5 years in the field. The focus will be on basic mechanisms of axon degeneration, disease relevance and potential therapeutic developments.

Objectives
  1. Identify the role of NMNAT2 and Sarm1 in Wallerian type axon degeneration.
  2. Describe the role of programmed axon degeneration pathway in distal axon degeneration seen in peripheral neuropathies.
  3. Restate the role of axon degeneration in different neurodegenerative disease models.

Registration

Early Registration: Thursday, September 19th  5:00- 6:00 PM
Registration: Friday, September 20th 8:00- 9:00 AM

LOCATION

Johns Hopkins Bloomberg Center
555 Pennsylvania Avenue
NW Washington, D.C. 20001

Johns Hopkins University opened a new state-of-the-art higher education facility on Pennsylvania Avenue in the heart of Washington, D.C. in 2023. The Johns Hopkins Bloomberg Center breaks the mold of higher education design and transforms iconic building into a multidisciplinary high-rise university. This modern and dynamic venue offers a sophisticated setting, providing an inspiring backdrop for the exchange of cutting-edge ideas and scientific discoveries. Conveniently situated, the venue allows attendees to explore the vibrant energy of the nation's capital during breaks and after sessions.

For those arriving by car, convenient parking is available at the garage located at 601 Pennsylvania Avenue NW, just across from the venue. Colonial Parking rates: Daily $26, Weekend flat rate: $14.95

For air travelers, the Ronald Reagan Washington National Airport (DCA) is the closest, providing easy access to the city. Alternatively, attendees can utilize Dulles International Airport (IAD) or Baltimore/Washington International Thurgood Marshall Airport (BWI), both offering efficient transportation options to downtown.

Washington, DC, boasts an extensive public transportation system, including the Metrorail and Metrobus, making it simple to navigate the city. The conference venue is within walking distance of several Metro stations, ensuring convenient access. Additionally, taxis, ride-sharing services, and rental cars are readily available for those preferring personalized transportation. Explore the vibrant capital with ease and make the most of your travel experience to this premier axon degeneration research event.

FEES
REGISTRATION CUT-OFF DATE: Friday, September 13, 2024

Register Online:
https://hopkinscme.cloud-cme.com/aph.aspx?P=5&EID=52443

Methods of Payment:  Learners must register and submit full payment prior to the start of the activity.  On-site payments can only be accepted if made by learners via credit card through the online portal by 5:00 p.m. ET on the first day of the activity.  The registration fee includes instructional materials, continental breakfasts, refreshment breaks, lunches, and dinners.

Registration .................................................................................... $ 550

You will receive a confirmation by e-mail.  If you have not received it by Friday, September 13, 2024, call (410) 502-9636 to confirm that you are registered.  A transcript of attendance will be available upon attestation of your credit hours and submission of the post activity online evaluation.   

The Johns Hopkins University reserves the right to cancel or postpone any activity due to unforeseen circumstances.  In this event, the University will refund the registration fee but is not responsible for travel expenses.   Additionally, we reserve the right to change the venue to a comparable venue.  Under such circumstances registrants will be notified as soon as possible.

LATE FEE AND REFUND POLICY
A $50 late fee applies to registrations received after 5:00 p.m. ET on  Friday, September 13, 2024.  A handling fee of $50 will be deducted for cancellation.  An additional fee may apply for cancellation of other events, including workshops and social activities.  Refund requests must be received by fax or mail by Friday, September 13, 2024.  No refunds will be made thereafter. Transfer of registration to another Johns Hopkins activity in lieu of cancellation is not possible. 


Accreditation
ACCREDITATION STATEMENT                                                                                                                                       

The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENT
The Johns Hopkins University School of Medicine designates this live activity for a maximum of 18 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The Johns Hopkins School of Medicine takes responsibility for the content, quality and scientific integrity of this CME activity.
Additional Information

Policy on PRESENTER and PROVIDER Disclosure
It is the policy of the Johns Hopkins School of Medicine that the presenter and provider globally disclose conflicts of interest. The Johns Hopkins School of Medicine OCME has established policies in place to identify and mitigate relevant conflicts of interest prior to this educational activity. Detailed disclosure will be made prior to presentation of the education.

SYLLABUS
The syllabus will be accessible online and via your mobile device in the CloudCME App prior to the activity. 

SOCIAL EVENT
A complimentary reception for registrants and faculty will be held  Thursday, September 19th 2024 at 6:00 pm (cocktail: 6:00 – 7:00 PM; EST dinner : 7:00 – 9:30 PM EST). Please indicate your attendance on the registration form.  NOTE: The commercial support received is solely for the educational component of this activity and will not be used to support this social event.

HOW TO OBTAIN CREDIT
Post activity, an online evaluation will be available to attendees to evaluate the activity and individual presentations and to identify future educational needs.  Upon completion of the evaluation, the learner must attest to the number of hours in attendance.  Credits earned will be added to the learner’s transcript and immediately available for print. The last day to access the evaluation and attest to your credits is Wednesday, November 6, 2024. 

An outcome survey will be sent to all physician attendees within two months post activity to assist us in determining what impact this activity had on the learner’s practice.

AMERICANS WITH DISABILITIES ACT
The Johns Hopkins School of Medicine fully complies with the legal requirements of the ADA and the rules and regulations thereof.  Please notify us if you have any special needs.

TO REGISTER or FOR FURTHER INFORMATION
Register Online
https://hopkinscme.cloud-cme.com/aph.aspx?P=5&EID=52443
Register by Phone                                           (410) 502-9636
Register by Fax                                               (866) 510-7088
Confirmation/Certificates/Transcripts           (410) 502-9636
General Information                                       (410) 955-2959
E-mail the Office of CME                              [email protected]

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Check out our mobile app CloudCME.
Organization Code: HopkinsCME                                                                                                                 

For technical assistance with website, CloudCME or credits, please visit our tech support help page: https://hopkinscme.cloud-cme.com/about/help

For general information, please visit the activity webpage at
https://hopkinscme.cloud-cme.com/aph.aspx?P=5&EID=52443

Acknowledgement
Applications for commercial support from health care related industries are pending.  A complete list of contributors will be provided in the syllabus.  Please note that commercial support received is solely for the educational component of the activity and will not be used to provide food and beverage.

Please note: The Physician Payments Sunshine Act was enacted by Congress to increase public awareness of financial relationships between drug and medical device manufacturers and physicians.  In compliance with the requirements of this Act, the commercial supporter/s of this activity may require the Johns Hopkins School of Medicine to report certain professional information (such as name, address, National Provider Identifier (NPI), and State License number) of physician attendees who receive complimentary food and beverage in conjunction with a CME activity.  The commercial supporter is required to submit the collected data to the Centers for Medicare and Medicaid Services which will then publish the data on its website.



Keywords: LIVE

HOTEL AND TRAVEL INFORMATION
A limited block of sleeping rooms has been reserved for your convenience and will be available on a first come, first served basis.

Hotel Registration Cut Off Date: 7/9/2024
Homewood Suites by Hilton Washington, D.C. Downtown
1475 Massachusetts Avenue NW, Washington, DC 20005, USA
Hotel Phone: 202-580-7348
Hotel Fax: 202-265-8010
Hotel Rate: $289.00

Hotel Registration Cut Off Date: 8/2/2024
Courtyard Washington Downtown/Convention Center
901 L Street NW, Washington, DC 20001, USA
Hotel Phone: 202-469-6357
Hotel Fax:
Hotel Rate: $249.00

Mitigation of Relevant Financial Relationships


Johns Hopkins University adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Bogdan Beirowski, MD, PhD
Associate Professor
Department of Neurology, College of Medicine, The Ohio State University
Robert W Burgess, PhD
Professor
The Jackson Laboratory
Alexandra Byrne, PhD
Assistant Professor
Department of Neurobiology, UMass Chan Medical School
Andrea Cortese, MD, PhD
Academic Neurologist
UCL Institute of Neurology, MRC Centre for Neuromuscular Disease
London, United Kingdom
Madeline Denton, BS
PhD Candidate
Johns Hopkins University School of Medicine Department of Neurology
Aaron DiAntonio, MD, PhD
Professor
Department of Developmental Biology Washington University School of Medicine
Julia Edgar, PhD
Professor
University of Glasgow
Marc Freeman, PhD
Director and Professor
Vollum Institute Oregon Health & Science University
Stefanie Geisler, MD
Assistant Professor
Washington University School of Medicine
Jonathan Gilley, PhD
Senior Research Associate
John van Geest Brain Repair Centre University of Cambridge
Cambridge, United Kingdom
Ahmet Hoke, MD, PhD
Johns Hopkins University
Erika Holzbaur, PhD, Professor
University of Pennsylvania Perelman School of Medicine
Vassilis Koliatsos, MD
Professor of Pathology, Johns Hopkins University School of Medicine
Claire Le Pichon, PhD
Investigator
Unit on the Development of Neurodegeneration National Institute of Health
Andrea Loreto, PhD
Research Fellow
University of Sydney, Save Sight Institute, School of Medical Sciences
Sydney, Australia
Sonia R Mayoral, PhD
Assistant Professor
Carney Institute for Brain Science, Brown University
Elisa Merlini, PhD
University of Cambridge
Cambridge, United Kingdom
Jeffrey Milbrandt, MD, PhD
Executive Director & James S. McDonnell Professor, Department of Genetics
McDonnell Genome Institute, Washington University School of Medicine
Brett M Morrison, MD
Associate Professor
Johns Hopkins University, SOM
Lyndsay Murray, PhD
Dr
University of Edinburgh
Edinburgh, United Kingdom
Clara Mutschler, PhD
University of Cambridge
Cambridge, United Kingdom
Lukas J Neukomm, PhD
Professor
University of Lausanne
Lausanne, Switzerland
Veselina Petrova, PhD
Dr
Boston Children's Hospital
Rosalind Segal, MD, PhD
Professor of Neurobiology
Harvard Medical School
Grace Shin, PhD
Assistant Professor
The Ohio State University
Michael Shy, MD
Professor Departments of Neurology, Pediatrics, and Neuroscience
University of Iowa Roy Carver School of Medicine
David J Simon, PhD
Assistant Professor
Weill Cornell Medicine
Ruth Stassart, MD
Professor
Leipzig University, Paul-Flechsig-Institute, Centre for Neuropathology and Brain Research
Leipzig, Germany
Jeremy M Sullivan, PhD
Assistant Professor of Neurology
Charlotte Sumner, MD
Professor of Neurology and Neuroscience
Johns hopkins
Vinod Sundaramoorthy, PhD, Research scientist
Research Fellow Viral Neuropathogenesis
Deakin University and CSIRO
Melbourne, Australia
Diana Tavares-Ferreira, PhD
UT Dallas
Gareth Thomas, PhD
Temple University
Pete Williams, PhD
Associate Professor
S:t Eriks Ögonsjukhus, Karolinska Institute, Solna, Sweden
Avraham Yaron, PhD
Weizmann Institute of Science
Rehovot, Israel
Stephan Zuchner, MD, PhD
Professor
Dr. John T. Macdonald Foundation Department of Human Genetics University of Miami

Friday, September 20, 2024
Syllabus - 8th International Axon Degeneration Conference
8:55AM - 9:00AM
Session 1: General Axon Degeneration Mechanisms - Regulators of Sarm1- Dependent Axon Degeneration
9:00AM - 9:35AM
Marc Freeman, PhD
Session 1: General Axon Degeneration Mechanisms - Shared Mechanisms of Axon Degeneration and Regeneration
9:35AM - 10:10AM
Alexandra Byrne, PhD
Session 1: General Axon Degeneration Mechanisms - Long-term survival of chronically demyelinated axons in a long-lived spontaneously demyelinating rat model of leukodystrophy
10:10AM - 10:30AM
Avraham Yaron, PhD
Session 2: General Axon Degeneration Mechanisms - Regulators of Sarm1-depdenent axon degeneration
10:45AM - 11:20AM
Aaron DiAntonio, MD, PhD
Session 2: General Axon Degeneration Mechanisms - From axon damage to disease: common mechanisms in neurodegeneration
11:20AM - 11:55AM
Claire Le Pichon, PhD
Session 2: General Axon Degeneration Mechanisms - Long-term survival of chronically demyelinated axons in a long-lived spontaneously demyelinating rat model of leukodystrophy
11:55AM - 12:15PM
Julia Edgar, PhD
Session 3: General Axon Degeneration Mechanisms - Axonal transport is disrupted by Parkinson’s disease-associated mutations in LRRK2
1:15PM - 1:50PM
Erika Holzbaur, PhD, Professor
Session 3: General Axon Degeneration Mechanisms - Translation defects, cell stress responses, and peripheral neuropathy
1:50PM - 2:25PM
Robert W Burgess, PhD
Session 3; General Axon Degeneration Mechanisms - Axon-T cell interactions that drive axon degeneration
2:25PM - 2:45PM
David J Simon, PhD
Session 4: Human Genetics - RFC1 repeat expansion causing sensory neuropathy and ataxia: from genetic identification to functional mechanisms
3:00PM - 3:35PM
Andrea Cortese, MD, PhD
Session 4: Human Genetics - CMT-SORD: a common axonal neuropathy from genetic discovery to therapy
3:35PM - 4:10PM
Stephan Zuchner, MD, PhD
Session 4: Human Genetics - Determining the role of SARM1-mediated axon degeneration in SMA
4:10PM - 4:30PM
Madeline Denton, BS
Session 5: Viruses and Toxins - Programmed axon death as a driver of toxic neuropathies: Insights into environmental neurotoxicity and opportunities for drug discovery
5:30PM - 6:05PM
Andrea Loreto, PhD
Session 5: Viruses and Toxins - Complex role of SARM1 in distinct modes of axonal degeneration induced by viral infections
6:05PM - 6:40PM
Vinod Sundaramoorthy, PhD, Research scientist
Session 5: Viruses and Toxins - Programmed axon death drives environmental neurotoxicity triggered by pyridine derivatives.
6:40PM - 7:00PM
Elisa Merlini, PhD
Saturday, September 21, 2024
Session 6: Axo-Glial interactions and Axon Degeneration - A Disabling Partnership: Chronic SARM1 Activation and Neuroinflammation
9:00AM - 9:35AM
Jeffrey Milbrandt, MD, PhD
Session 6: Axo-Glial interactions and Axon Degeneration - Myelin insulation as a potential risk factor for axonal survival in autoimmune demyelination
9:35AM - 10:10AM
Ruth Stassart, MD
Session 6: Axo-Glial interactions and Axon Degeneration - Sex-Specific Differences In Glia Neuro-Immune Interaction In Dorsal Root Ganglia In Bortezomib-Induced Neuropathy
10:10AM - 10:30AM
Stefanie Geisler, MD
Session 7: Axo-Glial interactions and Axon Degeneration - Protecting injured axons through glial metabolic responses
10:45AM - 11:20AM
Bogdan Beirowski, MD, PhD
Session 7: Axo-Glial interactions and Axon Degeneration - Local Impacts of Myelin on Wallerian Degenerationtitle
11:20AM - 11:55AM
Sonia R Mayoral, PhD
Session 7: Axo-Glial interactions and Axon Degeneration - Cell Autonomous and Non Cell Autonomous Regulators of the Schwann Cell Injury Response
11:55AM - 12:15PM
Clara Mutschler, PhD
Session 8: Axon Degeneration in Disease - Local translation sustains synaptic function in impaired Wallerian degeneration.
1:15PM - 1:50PM
Lukas J Neukomm, PhD
Session 8: Axon Degeneration in Disease - Neuroimmune Interactions In Chemotherapy-Induced Peripheral Neuropathy
1:50PM - 2:25PM
Grace Shin, PhD
Session 8: Axon Degeneration in Disease - Question and Answer
2:25PM - 2:45PM
Session 9: Axon Degeneration in Disease - A mechanistic approach to Chemotherapy-induced peripheral neuropathy
3:00PM - 3:35PM
Rosalind Segal, MD, PhD
Session 9: Axon Degeneration in Disease - New ideas on axonal degeneration: implications for traumatic brain injury and neurodegenerative disease
3:35PM - 4:10PM
Vassilis Koliatsos, MD
Session 9: Axon Degeneration in Disease - Multi-kinase inhibition as a common neuroprotective strategy against axonal neurodegeneration and neurotoxicity in different neurodegenerative contexts
4:10PM - 4:30PM
Veselina Petrova, PhD
Session 10: Axon Degeneration in Disease - Key regulators of programmed axon death as risk factors for ALS and other diseases
5:30PM - 6:05PM
Jonathan Gilley, PhD
Session 10: Axon Degeneration in Disease - Blood-neural barrier impairments drive TRPV4-mediated motor neuron degeneration
6:05PM - 6:40PM
Jeremy M Sullivan, PhD
Session 10: Axon Degeneration in Disease - Investigating axon degeneration and regeneration in mouse models of Spinal Muscular Atrophy
6:40PM - 7:00PM
Lyndsay Murray, PhD
Sunday, September 22, 2024
Session 11: Clinical Translation - Evaluating Axonal Degeneration in Patients with Inherited Neuropathy
9:00AM - 9:35AM
Michael Shy, MD
Session 11: Clinical Translation - Molecular Profiling of Human Peripheral Nerves provides new insights into Diabetic Neuropathy
9:35AM - 9:55AM
Diana Tavares-Ferreira, PhD
Session 11: Clinical Translation- Novel inhibitors of acute, axonal DLK palmitoylation are neuroprotective and avoid the deleterious side effects of cell-wide DLK inhibition
9:55AM - 10:30AM
Gareth Thomas, PhD
Break
10:30AM - 11:00AM
This session is not eligible for AMA PRA Category 1 Credit™- Session 12: Axo-Glial interactions and Axon Degeneration
11:00AM - 1:00PM
Conference Closing Remarks
1:00PM - 1:15PM
Ahmet Hoke, MD, PhD

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